Micropropagated and seed-born silver birches (Betula pendula Roth) were compared for survival, height growth and occurrence of biotic damage (voles, hares, mooses, stem lesions and cankers) in field trials in southern Finland. The material consisted of 11 clones and 10 different lots of seedlings growing in 10 field trials, established in clear-cut forest cultivation areas. The plants were 6–7 years old. The micropropagated and seed-born material types did not significantly differ from each other as regards survival, height growth and frequencies of damage caused by biotic agents. Large and significant differences were, however, detected in survival, height and frequencies of all types of biotic damage between single clones. Careful selection and testing of birch clones in field conditions is recommended before wide-scale commercial micropropagation and practical forest cultivation takes place.